Endocrine Research

Compounds studied in hormone signaling, including growth hormone, reproductive and pancreatic axes. Appearing here means a compound has been studied in this area, not that it works. Open a profile to see the type of evidence and its limits.

Abaloparatide

Synthetic 34-amino-acid analog of parathyroid hormone-related protein (PTHrP 1-34); parathyroid hormone type 1 receptor (PTH1R) agonist; anabolic (bone-forming) osteoporosis agent

ACTH (1-39)

Endogenous 39-amino-acid pituitary peptide hormone derived from pro-opiomelanocortin (POMC); melanocortin-2 receptor (MC2R) agonist with activity at other melanocortin receptors; adrenal steroidogenesis stimulator

Cagrilintide

Long-acting acylated amylin analogue; amylin and calcitonin receptor agonist

CJC-1295

Synthetic growth hormone-releasing hormone (GHRH/GRF) analogue; long-acting growth hormone secretagogue

CJC-1295 (no DAC)

Synthetic tetrasubstituted GHRH(1-29) analogue; short-acting experimental GHRH analogue

Delta Sleep-Inducing Peptide

Synthetic nonapeptide; experimental neuropeptide; sleep/stress-regulation research peptide

EPO (Erythropoietin)

Endogenous 165-amino-acid glycoprotein hormone (cytokine) produced mainly by the kidney; erythropoietin receptor (EPOR) agonist; erythropoiesis-stimulating agent (ESA)

Gonadorelin

Synthetic gonadotropin-releasing hormone; GnRH receptor agonist; hypothalamic reproductive hormone

Growth Hormone-Releasing Peptide-2

Synthetic hexapeptide; growth hormone secretagogue; ghrelin/growth hormone secretagogue receptor agonist

Growth Hormone-Releasing Peptide-6

Synthetic hexapeptide; growth hormone secretagogue; ghrelin/growth hormone secretagogue receptor agonist

HCG (Human Chorionic Gonadotropin)

Glycoprotein hormone; luteinizing-hormone receptor agonist; gonadotropin

Hexarelin

Synthetic hexapeptide; growth hormone secretagogue; ghrelin/growth hormone secretagogue receptor agonist

HGH (Somatropin)

Endogenous 191-amino-acid, 22-kDa pituitary polypeptide hormone; growth hormone receptor (GHR) agonist; approved recombinant hormone therapy

HMG (Human Menopausal Gonadotropin)

Urine-derived gonadotropin preparation from postmenopausal women containing follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity; FSH and LH/hCG receptor agonist; fertility (ovarian stimulation) medicine

IGF-1 DES

Naturally occurring truncated variant of insulin-like growth factor 1 lacking the N-terminal tripeptide Gly-Pro-Glu (67 amino acids); IGF-1 receptor agonist with markedly reduced IGF-binding-protein affinity

IGF-1 LR3

Engineered recombinant insulin-like growth factor-1 analogue; IGF-1 receptor agonist; reduced IGF-binding-protein-affinity analogue

Ipamorelin

Synthetic pentapeptide; growth hormone secretagogue; ghrelin receptor / growth hormone secretagogue receptor agonist

Kisspeptin-10

Endogenous kisspeptin fragment; KISS1R/GPR54 agonist; reproductive neuroendocrine peptide

Oxytocin

Endogenous cyclic nonapeptide hormone; neuropeptide; oxytocin-receptor agonist

Pancragen

Synthetic tetrapeptide; insulinotropic-peptide mimetic; experimental pancreatic/endocrine bioregulator

Pramlintide

Synthetic amylin analogue; amylin receptor agonist; pancreatic hormone analogue

Prostamax

Synthetic tetrapeptide; short peptide bioregulator; experimental prostate-associated peptide

PT-141

Synthetic cyclic melanocortin peptide; melanocortin receptor agonist; centrally acting sexual-function drug

Sermorelin

Synthetic 29-amino-acid growth hormone-releasing hormone fragment; GHRH receptor agonist; growth-hormone secretagogue

Teriparatide

Recombinant 34-amino-acid N-terminal fragment of human parathyroid hormone; PTH1 receptor agonist; bone-forming (anabolic) osteoporosis drug

Tesamorelin

Synthetic growth hormone-releasing hormone (GHRH/GHRF) analogue; growth hormone secretagogue

Testagen

Research-market short peptide bioregulator; purported testicular/reproductive-associated tetrapeptide

Triptorelin

Synthetic decapeptide gonadotropin-releasing hormone (GnRH/LHRH) agonist analog; hormonal therapy agent